PiRNA


PiRNA (正體)

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piRNA全名Piwi-interacting RNA,是一类小型RNA分子,长度大约是29到30个核苷酸。只表现在哺乳动物睾丸中,并且可以和Piwi蛋白结合形成piRNA复合物(piRNA complexes,piRCs)。与RNA沉默(RNA silencing)作用有关。

相关文献

  • N.C. Lau et al., "Characterization of the piRNA Complex from Rat Testes," Science 313, 363 (2006)
  • V.N. Kim, "Small RNAs Just Got Bigger: Piwi-Interacting RNAs (piRNAs) in Mammalian Testes," Genes Dev. 20, 1993 (2006)
  • A. Girard et al., "A Germline-Specific Class of Small RNAs Binds Mammalian Piwi Proteins," Nature 442, 199 (2006)
  • A. Aravin et al., "A Novel Class of Small RNAs Bind to MILI Protein in Mouse Testes," Nature 442, 203 (2006)
  • S.T. Grivna et al., "A Novel Class of Small RNAs in Mouse Spermatogenic Cells," Genes Dev. 20, 1709 (2006)
      
主要生物化学物质种类
| 氨基酸 | 核酸 | 糖类 | 核苷糖 | 脂类 | 萜类 | 类胡萝卜素 | 四吡咯 | 辅因子 | 类固醇 | 类黄酮 | 生物碱 | 聚酮 | 配糖类
Analogues of nucleic acids: 核酸类型 Analogues of nucleic acids:
碱基 嘌呤腺嘌呤/鸟嘌呤) | 嘧啶尿嘧啶/胸腺嘧啶/胞嘧啶
核苷 腺苷/去氧腺苷 | 鸟苷/去氧鸟苷 | 尿苷 | 胸苷 | 胞苷/去氧胞苷
核苷酸 AMP/UMP/TMP/GMP/CMP | ADP/UDP/TDP/GDP/CDP | ATP/UTP/TTP/GTP/CTP | cAMP/cGMP/cADPR
去氧核苷酸 dAMP/dTMP/dGMP/dCMP | dADP/dTDP/dGDP/dCDP | dATP/dTTP/dGTP/dCTP
核糖核酸 RNA | mRNA | piRNA | tRNA | rRNA | ncRNA | gRNA | shRNA | siRNA | snRNA | miRNA | snoRNA
去氧核糖核酸 DNA | mtDNA | cDNA | 质体 | 黏质体 | BAC | YAC | HAC
核酸相似物 GNA | PNA | TNA | LNA | Morpholino






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